Graft-versus-host-disease (GVHD) can cause physical problems that interfere with a person's ability to manage daily tasks. Physical Medicine and Rehabilitation (PM&R) physicians, also known as physiatrists, can diagnose why a person is experiencing pain or decreased physical functioning and direct them to the correct specialist to address these problems.

Occupational therapists can help transplant recipients manage their fatigue, and redesign their lifestyle to improve quality of life, while recovering transplant and side effects such as graft-versus-host disease (GVHD).